Guidance

CladeMpox: I mpox: affected countries

This page provides an overview of countries reporting clade I mpox casesepidemiology, (historic or current), indicating where there may be a risk of clade I and clade II mpox exposure.

Global overview

TheThere are 2 major genetic groups (clades) of MPXV, clade I mpox(formerly outbreakknown isas focusedCentral inAfrican aor numberCongo ofbasin countriesclade) withinand theclade AfricanII region,(formerly known as perWest FigureAfrican 1clade). below.Clade ImportedI cladeis Isplit mpoxinto casesclade outsideIa theand Africanclade regionIb. haveClade beenII reportedis insplit severalinto countries.

Figureclade 1.IIa Africanand regionclade countriesIIb, reportingand laboratoryall confirmedclades cladehave Isubgroup mpoxclusters (historiccalled orlineages. current)

The situationmajority mayof changethe rapidlycases seen in differentthe countries.global Itoutbreak iswhich possiblestarted thatin 2022 were from clade IIb, lineage B.1. The latest epidemiological data on mpox cases(all mayclades) can be presentfound inon countriesthe whoWorld haveHealth notOrganization reported(WHO) cladempox Isurveillance mpoxdashboard.

Figure to1. date.Geographic Mpoxdistribution of anMPXV unknownclades, cladeby hascountry, beenas reportedof in13 GabonMarch but2025 is(adapted presumedfrom tothe beWorld cladeHealth IOrganization (duemulti-country toexternal casesituation travelreport). history).

GivenThe themap continuingis spreadnot indicative of cladeongoing Ioutbreaks mpox,and pleaseis checkgenerated thisfrom webpage regularlyavailable forlaboratory anydata updatesassociated towith theboth countriestravel-associated included.

and locally acquired cases.

Table 1. ListCountries ofreporting countriesthe withhighest evidencenumber of ongoingrecent cladempox Icases (all clades). Adapted from WHO Global mpox transmissiontrends, orupdated exportation2 duringMarch the2025. 2024Data toas 2025of outbreak31 January 2025

Country EvidenceCases ofin transmissionthe past month CladeTotal confirmed casesClades reported
BurundiCommunityDemocratic transmissionIb
Central African RepublicCommunity transmissionIa
Democratic Republic of the Congo Community transmission1,651 17,820Clades Ia and Ib
GabonUganda Community transmission1,022 I2,430Clade Ib
KenyaBurundi Community transmission342 3,288Clade Ib
Republic of the CongoAustralia Community transmission90 Ia1,644Clade and IbII
RwandaBrazil Community transmission63 Ib13,579
SouthClades SudanUnclearIb (historicaland community transmission)IIIa
TanzaniaGermany Unclear494,139Clades (evidenceIb ofand exported cases)IIIb
UgandaChina Community transmission41 Ib2,847
UnitedClades ArabIb EmiratesUnclearand (evidence of exported cases)IIIb
ZambiaSpain Community transmission33 Ib8,514

Table 2. List of countries in the African region with historical transmission of clade I mpox, with no cases reported during the 2024 to 2025 outbreak

CountryEvidence of transmissionClade II
CameroonUnited States Community transmission28 Ia34,715Clades Ib and II
SudanItaly Community transmission22 Ia1,109Clade II

Imported

Clade clade I mpox casesoutbreak: with2024 limitedto or no onward transmission have been reported in several countries:

2025

  • Angola

    On (with14 reportedAugust travel2024, historythe toWHO adeclared clade I affected country)

  • Belgium (with reported travel history to a cladePublic IHealth affectedEmergency Africanof country),International withConcern limited transmission among household contacts
  • Brazil (webpage in Portuguese)response (with reported travel history to the Democraticupsurge Republic of the Congo)
  • Canada (with reported travel history to a clade I affectedmpox Africanin country)
  • China (with reported travel history to the Democratic Republic of the Congo and Uniteda Arabgrowing Emirates),number withof limitedcountries transmissionin amongthe closeAfrican contacts
  • FranceRegion. (withThis reportedoutbreak travelremains historyongoing, towith aevidence cladeof Isustained affectedcommunity Africantransmission country),in withseveral limitedcountries, transmissionas amongper closeTable contacts
  • Germany has2.

    Travel-associated reported imported clade I mpox cases (withoutside reportedthe travelAfrican historyRegion tohave Rwanda,been Tanzaniareported orin otherseveral cladecountries. IWhilst affectedthere Africanis countries),currently withno limitedevidence transmissionof amongsustained householdcommunity contacts

  • India (withtransmission reportedof travelclade historyI tompox theoutside United Arab Emirates)
  • Republic of IrelandAfrican (withRegion reportedcountries, travellimited historylocal totransmission the(for Democraticexample, Republichousehold oftransmission) thehas Congo)
  • Oman (withbeen reported travelin historyBelgium, toChina, theFrance, United Arab Emirates)
  • PakistanGermany (withand reported travel history to the United Arab Emirates)
  • QatarKingdom.

    Figure (with2. reportedAfrican travelregion historycountries toreporting Uganda)

  • Southlaboratory Africaconfirmed (withclade reportedI travelmpox history(historic toor Uganda)
  • Sweden (withcurrent)

    Mpox reportedof travelan historyunknown to a clade Ihas affectedbeen Africanreported country)

  • Thailand (within reportedGabon travelbut historyis presumed to abe clade I affected(due Africanto country)
  • Unitedcase States (with reported travel historyhistory).

    Table to2. aCountries cladewith Ievidence affectedof Africanongoing country)

  • the United Kingdom has reported imported clade I mpox casestransmission (withor reportedexportation travelduring historythe 2024 to clade2025 Ioutbreak
  • Zimbabwe
  • CountryEvidence affected countries in Africa), with limited of transmission among household contactsClade
    BurundiCommunity (withtransmissionIb
    Central reportedAfrican travelRepublicCommunity historytransmissionIa
    Democratic toRepublic Tanzania)

    Theseof countriesthe areCongo

    Community nottransmissionIa consideredand asIb
    GabonCommunity clade transmissionI
    KenyaCommunity mpoxtransmissionIb
    Republic affected for purposes of testingthe orCongoCommunity guidance,transmissionIa unlessand anIb
    RwandaCommunity individualtransmissionIb
    South reportsSudanUnclear being(historical acommunity contacttransmission)Ia
    TanzaniaUnclear of(evidence a confirmed case in one of theseexported cases)Ib
    UgandaCommunity countries.transmissionIb
    United ReportedArab travelEmiratesUnclear history(evidence is not necessarily indicative of acquisitionexported cases)Ib
    ZambiaCommunity in-country and investigations may be ongoing.

    transmission
    Ib

Updates to this page

Published 14 October 2024
Last updated 1117 March 2025 + show all updates
    1. Added entries for Brazil and Qatar.

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