Guidance

Get more help to apply for medicines Integrated Scientific Advice (ISA)

Extra information for the Medicines and Healthcare products Regulatory Agency (MHRA) and National Institute for Health and Care Excellence (NICE) Integrated Scientific Advice (ISA) service.

From:
Medicines and Healthcare products Regulatory Agency and National Institute for Health and Care Excellence
Published
20 February 2026

Documents

Writing good questions for Integrated Scientific Advice (ISA)

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Creating an ISA briefing book

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Find out about fees for the ISA service

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Getting the most from your ISA meeting

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Understanding your ISA report

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All Integrated Scientific Advice (ISA) service application questions

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MHRA and NICE Integrated Scientific Advice briefing book template

MS Word Document, 4.57 MB

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Details

This service offers a coordinated approach from the the MHRA and NICE to regulatory and health technology assessment (HTA) advice for medicine developers. See specific information on:

  • good questions for the ISA service

  • documents you need to prepare

  • fees

  • presenting at an ISA meeting

  • ISA service reports

Updates to this page

Published 20 February 2026

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