Bluetongue serotype 3 (BTV-3) vaccination

There are 3 bluetongue serotype (BTV-3) vaccines thatauthorised canfor beuse used in Greatthe Britain. These are:UK:

• Bluevac-3
• Bultavo 3BULTAVO 3
• SYVAZULSyvazul BTV 3

WhereGuidance youfor cankeepers 

Deciding usewhether BTV-3to vaccines

vaccinate 

InWork England,with youyour canvet useto thedetermine Bluevac-3,if bluetongue  vaccination Bultavois 3right orfor SYVAZULyour BTVanimals.  

You 3can vaccines,also ascheck longthe Battle asBluetongue youcampaign for complymore withinformation theon deciding conditionswhether ofto thevaccinate generalyour licenceanimals. 

Administering forvaccines

A vet Englandmust includingprescribe reportingBTV-3 vaccination activity.vaccines.

InAs Scotland,the animal keeper, you can useadminister the Bluevac-3,vaccine Bultavoto 3your oranimals.

You SYVAZULshould use BTVsafe 3practice, vaccines,based ason longthe ascode youof complypractice withon the declarationresponsible includinguse reportingof vaccinationanimal activitymedicines on the farm..  

Reporting vaccinations and keeping records

In Wales,England, youWales canand useScotland theyou Bluevac-3,must:   

• keep Bultavoa 3record orof SYVAZULevery BTVanimal 3you vaccines,vaccinate as– longthe asinformation you complyneed withto therecord conditionsis on ofthe general thelicence for England, general licence for Wales includingor reportingdeclaration vaccinationfor activityScotland.

  In

• keep Northernthese Ireland,records youfor canat useleast the5 Bluevac-3,years  
• report Bultavovaccinations 3within or48 SYVAZULhours BTV– 3providing vaccines,details asincluding longthe asindividual animal IDs and vaccine you use

In Northern Ireland you must:

• apply for a specific licence forto Northernobtain IrelandBluetongue andvaccines (DAERA)
• report vaccinationvaccinations activityto DAERA.
  within 5 working days of vaccinating

AdvisoryGuidance note for vets

The UK, Wales, Scotland and Northern Ireland Chief Veterinary Officers ask all vets to record BTV-3 vaccine vaccine use and inform relevant authorities of any adverse effects.effects. 

Veterinarians should read the relevant advisory note for their country before prescribing any any BTV-3 vaccine: vaccine.

Read the:

• advisory note for England
• advisory note for Wales
• advisory note for Scotland
• advisory note for Northern Ireland

Market authorisation 

TheseVets vaccinesin wereEngland, authorisedScotland underand exceptionalWales circumstancesshould andnotify thereforeDefra assessmentswithin were7 baseddays onof customisedprescribing requirementsthe forvaccine documentation.

Transitionusing periodthe prescription forof permittedthe BTV-3 vaccine vaccines

reporting form.

MarketingVets authorisationsin forNorthern Ireland should record BTV-3 vaccine vaccinesuse haveeach beenmonth and grantedreturn forthe usecompleted inrecord Greatto Britaintheir andlocal NorthernDAERA Ireland.Direct Office.

Market authorisation 

UnauthorisedMarketing authorisations for BTV-3 vaccines (Bluevac-3, vaccinesBULTAVO 3 permittedand Syvazul) have been granted for use subjectin toGreat licenceBritain orand declarationNorthern can:Ireland.

• be

  Transition importedperiod intofor Greatunauthorised Britainvaccines

  Unauthorised (England,vaccines Scotlandthat andwere Wales)imported under a permit untilbefore October 2025

• be imported into NorthernGreat IrelandBritain under(31 aDecember permit2025 untilfor 31Northern DecemberIreland) 2025

• can continue to be usedused, underproviding:

  a) the permitlicence or untildeclaration conditions theyare reachmet 

  b) the vaccine theirhas expirynot date,exceeded its expiry asdate 

  c) the vaccine longwas purchased on as they were purchased on the Great BritainBritain or Northern and Northern Ireland markets

You can use authorised vaccines as soon as they are available.

Bluevac-3 suspension for injection for sheep and cattle

Permitted Bluevac-3 product information

ForThe themarketing permittedauthorisation Bluevac-3 product for use during the transition period, you can view the:

• summary of product characteristics for Bluevac-3 BTV-3 vaccine in the UK
• permit for use of Bluevac-3 bluetongue serotype 3 vaccine in the UK

Authorised Bluevac-3 product information

The marketing authorisation for this vaccine is held by CZ Veterinaria S.A.

This vaccineIt has has marketing authorisations for use in Great Britain and Northern Ireland,Ireland.  

This andvaccine is for is for the active immunisation of:of: 

• sheep - to reduce the viraemia, mortality and clinical signs caused by the serotype 3 of the bluetongue virusvirus 
• cattle - to reduce the viraemia against the serotype 3 of the bluetongue virus

TheFind the summary of product characteristics (SPC) for the authorised Bluevac-3 productproduct:

• for Great isBritain - on available on the the VMD’s Product Information Database (PID).

  Bultavo

• for 3Northern suspensionIreland - on forthe European injectionMedicines forAgency sheep(EMA)’s andUnion cattleProduct database

Permitted

Find Bultavoinformation 3on productunauthorised Bluevac-3 vaccine information

Forthat thewas permittedimported Bultavounder 3permit productbefore forOctober use2025 duringinto theGreat transitionBritain period,(31 youDecember can2025 viewfor the:Northern Ireland):

• summary of product characteristics for Bultavo 3 Bluevac-3 BTV-3 vaccine vaccine in the UK 
• permit for use of BultavoBluevac-3 3 bluetongue serotype 3 vaccine in the UK

Authorised

BULTAVO 3 Bultavosuspension 3for productinjection information

for sheep and cattle

The marketing authorisation for thisthe BULTAVO 3 vaccine is held by Boehringer Ingelheim Animal Health UK Limited.

ThisLimited. It vaccine has marketing authorisations for use in Great Britain and Northern Ireland,Ireland.

This andvaccine is for the active immunisation of:of: 

• sheep - to reduce viraemia and to prevent clinical signs caused by by BTV-3  
• cattle - to prevent viraemia and to prevent clinical signs caused by by BTV-3  

TheFind the summary of product characteristics (SPC) for the authorised BultavoBULTAVO 3 3 product is available on the the VMD’s Product Information Database (PID) and the European Medicines Agency (EMA)’s Union Product database.. 

SYVAZUL

Find BTVinformation 3on suspensionunauthorised BULTAVO for3 vaccine injectionthat forwas sheepimported andunder cattle

Permittedpermit Syvazulbefore productOctober information 

For2025 theinto permittedGreat SyvazulBritain product(31 forDecember use2025 duringfor theNorthern transition period, you can view the:  Ireland): 

• summary of product characteristics forfor BULTAVO 3  vaccine SYVAZUL BTV 3 vaccine in the UK 
• permit for use of SYVAZULBULTAVO 3  vaccine BTV 3 bluetongue serotype 3 vaccine in the UK

Authorised

Syvazul product- information

BTV 3 suspension for injection for sheep and cattle

The marketing authorisation for thisthe Syvazul vaccine is held by Laboratorios SYVA S.A.U.

ThisS.A.U. It has vaccine has marketing authorisations for use in Great Britain and Northern Ireland.

TheThis Greatvaccine Britain authorised product is for the active immunisation of:of: 

• sheep - to reduce viraemia, mortality, clinical signs and lesions caused by bluetongue serotype 33 
• cattle - to reduce viraemia caused by bluetongue virus serotype 3

TheFind the summary of product characteristics (SPC) for thethe authorised Syvazul BTV GB-authorised SYVAZUL BTV 3 isproduct: 

• for availableGreat onBritain the -  on the VMD’s Product Information Database.

  SYVAZUL 

• for BTVNorthern 3Ireland is- on authorisedthe European throughoutMedicines theAgency EU(EMA)’s andUnion accordingProduct to the Windsor Frameworkdatabase

Find couldinformation beon marketedunauthorised Syvazul BTV in3 vaccine Northernthat Ireland,was forimported theunder activepermit immunisationbefore ofOctober sheep2025 tointo reduceGreat viraemia,Britain mortality,(31 clinicalDecember signs2025 andfor lesionsNorthern caused by bluetongue serotype 3.Ireland):

The

• summary of product characteristics (SPC)for Syvazul BTV for3 thevaccine EU-authorisedin SYVAZULthe BTVUK  
• permit 3for isuse availableof Syvazul BTV on3 the VMD’sbluetongue Productserotype Information3 Databasevaccine andin the European Medicines Agency (EMA)’s Union Product databaseUK.

MovementBluetongue controls and trade restrictionstesting

All trade restrictions still apply to vaccinated animals. You should not test vaccinated animalsanimals within 7 asdays partof vaccination. ofAny sample ataken less pre-movementthan test7 indays after bluetonguevaccination could zoneslead untilto 7false dayspositive afterresults.

Read theirmore vaccination.about Thisbluetongue will prevent interference with BTV-3 monitoring.testing.