Immunoglobulin: when to use
UK Health Security Agency's immunoglobulin handbook, providing guidance on administering immunoglobulin to prevent serious disease.
- From:
- UK Health Security Agency
- Published
- 1 October 2008
- Last updated
-
719NovemberMay20242025 — See all updates
Applies to England
Documents
Details
Human Rabies Immunoglobulin (HRIG)
Further advice about post-exposure rabies treatment, supply and administration of rabies vaccine and immunoglobulin please see guidance for rabies post-exposure prophylaxis.
Measles post-exposure prophylaxis
For guidance on the use of post-exposure prophylaxis for measles in high-risk groups please see guidance for measles post-exposure prophylaxis.
Tetanus immunoglobulin
For guidance on the treatment of tetanus cases and management of tetanus prone wounds, please see tetanus: guidance for health professionals.
Post exposure prophylaxis for chickenpox and shingles
For the latest guidance, please see the guidelines on post exposure prophylaxis (PEP) for chickenpox and shingles
Immunoglobulins are concentrated antibody preparations that provide immediate short-term protection against disease for individuals at high risk of severe disease or serious complications from the disease.
These documents contain information, indications and guidance for the use of immunoglobulin preparations for each individual disease.
Details
Human Rabies Immunoglobulin (HRIG)
Further advice about post-exposure rabies treatment, supply and administration of rabies vaccine and immunoglobulin please see guidance for rabies post-exposure prophylaxis.
Measles post-exposure prophylaxis
For guidance on the use of post-exposure prophylaxis for measles in high-risk groups please see guidance for measles post-exposure prophylaxis.
Tetanus immunoglobulin
For guidance on the treatment of tetanus cases and management of tetanus prone wounds, please see tetanus: guidance for health professionals.
Post exposure prophylaxis for chickenpox and shingles
For the latest guidance, please see the guidelines on post exposure prophylaxis (PEP) for chickenpox and shingles
Immunoglobulins are concentrated antibody preparations that provide immediate short-term protection against disease for individuals at high risk of severe disease or serious complications from the disease.
These documents contain information, indications and guidance for the use of immunoglobulin preparations for each individual disease.
Updates to this page
Sign up for emails or print this page
Update history
2025-08-19 12:16
Added new ‘Information for patients on the prevention of diseases using immunoglobulin’ publication and updated ‘Administration of HNIG for measles post-exposure prophylaxis’.
2025-08-14 09:22
Updated ‘Rabies and Immunoglobulin Service (RIgS)’.
2025-06-04 14:34
Added telephone contact number for Rabies and Immunoglobulin Service (RIgS).
2025-05-19 14:00
Updated ‘Rabies and Immunoglobulin Service (RIgS)’.
2024-11-07 15:08
Removed ‘Immunoglobulins – how and when to issue out of hours’.
2024-07-01 11:00
Added ‘Administration of HNIG for measles post-exposure prophylaxis’ and updated General product information and how to administer immunoglobulin (issued August 2020) include HNIG for measles.
2024-02-20 10:05
Added ‘Hepatitis A immunoglobulin (issued 2024)’.
2023-11-14 13:28
Updated Post-exposure for non-responders section in Hepatitis B immunoglobulin.
2022-09-26 16:26
Updated hepatitis B immunoglobulin.
2022-05-04 15:37
Updated Diphtheria anti-toxin: clinical guidance.